Results 121 to 130 of about 237,874 (311)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Perceptions of e- marketing, social media, individuals and purchase intention – what can we learn from research? [PDF]
Social media began as a tool for people to communicate, engage socially and play. Although the enthusiasm in social media initially began with the younger age group, the interest has expanded to others as well. In the last two or three years, the role of
Mobasheri, Sahar, Norshidah, Mohamed
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Relationship Quality, Relationship Value, Purchasing Intention: An Empirical Study in the Retail Industry in the USA, Japan and Taiwan [PDF]
, 2011 [[abstract]]Due to the increasing globalization of the marketplace, understanding consumer culture has become a most critical issue. The purpose of this study is to review the past literature and propose a model of “quality-value-purchasing intention ...
JAY M. WU, KUAN-I WANG, DONG-JENN YANG
core
Integrated Marketing Communications and Their Effects on Customer Switching Intention
, 2016 This research investigates the path from integrated marketing communications to switching cost, satisfaction, commitment, and switching intention among mobile telecommunications customers. This research is based on extant literature that brand awareness,
Thaichon, Paramaporn +3 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
BMC Public HealthBackground Healthcare staff in China, especially females, work in a high-pressure, high-load, and high-risk environment, which affects the physical and mental health, the efficiency and quality of work, and increases turnover intention. The present study
Dongling Yuan +7 more
doaj +1 more source
The relationship between transformational leadership, employee engagement and intention to quit among employees at a selected organisation [PDF]
, 2020 Masters of CommerceOrganisations should focus their attention on strategies that mitigate the intention to quit of employees, this can be achieved through creating an environment that is favourably disposed to an efficient and engaged workforce and by ...
Swartz, Natasha Lizette
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source