Results 41 to 50 of about 1,291,418 (265)

Species Composition and Growth Pattern of a Multi-Species Grouper in Kwandang Bay, Sulawesi Sea, Indonesia

open access: yesJurnal Ilmiah Perikanan dan Kelautan, 2023
Highlight Research • There are 26 species identified to be originated from the bay, which the highest diversity in Indonesia • Six species found in Kwandang Bay is showing trends of decreasing populations and two species vulnerable based on IUCN ...
Dewi Shinta Achmad   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Length-weight and length-length relationships and condition factor of Alburnus chalcoides (Güldenstädt, 1772) populations from rivers of the southern Caspian Sea [PDF]

open access: yesبوم‌شناسی آبزیان, 2021
In This study, the length-weight and fork-total length relationships, growth pattern and condition factor of Alburnus chalcoides, was estimated during 2006-2007. A total of 170 specimens were collected from the Chelvand, Khalehsara, Siahdarvishan, Sefid,
Atta Mouludi-Saleh   +2 more
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Biometric analysis of Oncorhynchus mykiss (Walbaum, 1792) and Salmo trutta, Linnaeus, 1758 from the different habitat in Himachal Pradesh

open access: yesScientific Reports
Biometric analysis offered important information on growth patterns, population differentiation, and habitat effects in trout. The present study aimed to evaluate variations among diverse ecological conditions and growth patterns across three farm sites ...
Hishani Kumari   +7 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Sex-Specific Vulnerability of Fish to Dredging in the Mediterranean Coastal Lagoon (Lake Manzala, Egypt)

open access: yesAquatic Sciences and Engineering
Lagoon dredging disrupts aquatic ecosystems and fish populations. A study in Lake Manzala, Egypt, assessed these impacts by analyzing 2616 fish across ten species.
Azza El-ganainy   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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