Results 81 to 90 of about 3,054,956 (233)

Is There a Unique Physical Entropy? Micro versus Macro [PDF]

, 2012
Entropy in thermodynamics is an extensive quantity, whereas standard methods in statistical mechanics give rise to a non-extensive expression for the entropy. This discrepancy is often seen as a sign that basic formulas of statistical mechanics should be
Dieks, D.G.B.J., History and Foundations of Science, Dieks, Dennis, Sub Foundations&PhilosophyofNaturSc begr, Andersen, Hanne   +4 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Minimal Entropy and Entropic Risk Measures: A Unified Framework via Relative Entropy

Risks
We introduce a new coherent risk measure, the minimal-entropy risk measure, which is built on the minimal-entropy σ-martingale measure—a concept inspired by the well-known minimal-entropy martingale measure used in option pricing.
Moritz Sohns
doaj   +1 more source

Modeling Small Systems Through the Relative Entropy Lattice

IEEE Access, 2019
There are certain contexts, where we would like to analyze the behavior of small interacting systems, such as sports teams. While large interacting systems have drawn much attention in the past years, let it be physical systems of interacting particles ...
Yair Neuman, Dan Vilenchik
doaj   +1 more source

How biased are maximum entropy models? [PDF]

, 2011
Maximum entropy models have become popular statistical models in neuroscience and other areas in biology, and can be useful tools for obtaining estimates of mutual information in biological systems.
Peter E. Latham, Latham, P., Macke, Jakob H., Iain Murray, Murray, I., Murray, Iain; id_orcid, Latham, Peter E., Jakob H. Macke, Macke, J.   +8 more
core  

On integrating size and shape distributions into a spatio-temporal information entropy framework [PDF]

, 2019
Understanding the structuration of spatio-temporal information is a common endeavour to many disciplines and application domains, e.g., geography, ecology, urban planning, epidemiology.
Christophe Claramunt, Claramunt, C., LEIBOVICI, Didier, Leibovici, D.G., Didier G. Leibovici, CLARAMUNT, Christophe   +5 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Optimising the relative entropy under semidefinite constraints

npj Quantum Information
Finding the minimal relative entropy of two quantum states under semidefinite constraints is a pivotal problem located at the mathematical core of various applications in quantum information theory.
Gereon Koßmann, René Schwonnek
doaj   +1 more source