Results 121 to 130 of about 3,736,035 (302)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Effects of seeding methods and nutrient management practices on growth and yield of organic wheat (Triticum aestivum)

The Indian Journal of Agricultural Sciences
An experiment was conducted out during winter (rabi) seasons of 2021–22 and 2022–23 at the Research Farm of Maharana Pratap Univesity of Agriculture and Technology, Udaipur, Rajasthan to study the effect of nutrient management practices and sowing ...
ADARSH SHARMA, S K SHARMA, ROSHAN CHOUDHARY, GAJANAND JAT, LATIKA VYAS, SHARVAN KUMAR YADAV   +5 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Dynamic Modeling of Agricultural Fresh and Dry Biomass Under Variable Nutrient Supply

Agriculture
Data-driven empirical models, including those based on reaction kinetics, are well-regarded for their ability to make accurate predictions and uncover underlying relationships.
Andrew Sharkey, Asher Altman, Yuming Sun, Yongsheng Chen   +3 more
doaj   +1 more source

Relative Backwardness and Technological Catching Up with Scale Effects [PDF]

This paper theoretically and empirically analyzes the sources of the observed pattern that the levels and growth rates of technology are different across countries. The model is extended version of endogenous growth models with catching up model which is
Sung Jin Kang
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Characterization of indigenous populations of cannabis in Iran: a morphological and phenological study

BMC Plant Biology
Background Cannabis is a historically, culturally, and economically significant crop in human societies, owing to its versatile applications in both industry and medicine.
Mehdi Babaei, Hossein Nemati, Hossein Arouiee, Davoud Torkamaneh   +3 more
doaj   +1 more source

Discounting and Relative Consumption [PDF]

This paper analyzes optimal social discount rates where people derive utility from relative consumption. We identify and compare three separate discount rates -- the social rate (taking positional externalities into account), the private rate, and the ...
Johansson-Stenman, Olof, Sterner, Thomas
core  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source