Effects of Different Plant Growth Regulators on Growth Physiology and Photosynthetic Characteristics of <i>Pinus koraiensis</i> Seedlings. [PDF]
Zhang W +9 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Identifying the demographic pathways linking environmental covariates to population dynamics in an avian migrant. [PDF]
Martin EC +4 more
europepmc +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Temperature outweighs diet in shaping developmental performance in two cricket species via growth delays and physiological limits. [PDF]
Vadboncoeur É +3 more
europepmc +1 more source
TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Effects of Macronutrients in Ten Different Plant Species on the Food Choice and Growth Performance of <i>Achatina fulica</i>. [PDF]
Tang K, Zheng Z, Lu X, Han Z, Sun S.
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Morpho-physiological traits and yield quality for cassava genotypes planted under drought during canopy establishment. [PDF]
Ittipong P +6 more
europepmc +1 more source

