Results 111 to 120 of about 24,021,736 (284)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The Kansas Information Technology Architecture
, 2009 Version 11.2; application/pdf; Cover title.; "12/28/2009."; "This Architecture provided to the State of Kansas by the Kansas Technical Architecture Review Board (KTARB), presented to and approved by the Information Technology Executive ...
Kansas. Information Technology Office.
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Tellus A: Dynamic Meteorology and Oceanography, 2007 The relative entropy is compared with the previously used Shannon entropy difference as a measure of the amount of information extracted from observations by an optimal analysis in terms of the changes in the probability density function (pdf) produced by the analysis with respect to the background pdf.
openaire +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Explanation, unification, and content [PDF]
, 1994 The following is an essay on the notion of scientific explanation as unification. In it a new notion of (logical) content is used to explicate Michael Friedman's notion of "k-atomicity," and to explicate the notion of the surplus content of hypothesis h ...
Gemes, Ken
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‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
The Usefulness of the Most Widely Reported Dutch Financial Statement Numbers to Stock Market Investors [PDF]
Much of the literature on the usefulness of company financial statement information focuses on the United States and the United Kingdom. But, these two countries are characterized by similar and rigid regulatory and enforcement regime.
Kabir, M.R.
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Tong Hao—an Asian Vegetable Expanding in Florida
EDIS, 2016 Tong Hao (Glebionis coronaria) is a member of the daisy family and therefore a relative of lettuce. It is an important vegetable in Asian communities.
Guodong Liu +4 more
doaj +2 more sources