Results 181 to 190 of about 24,021,736 (284)

Syllabus Information and the Relative Importance of Content They Can Contain

College Teaching
openaire   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Effect of Drying Temperature and Storage Time on the Fatty Acid Composition and Lipid Indices in Wild Edible King Bolete Mushroom (<i>Boletus edulis</i>). [PDF]

Molecules
Šnirc M, Jančo I, Jakabová S, Golian J, Mleczek M, Árvay J.   +5 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Dynamic mechanical properties of MREs under the coupled effect of magnetic field, normal force, and CIP content. [PDF]

iScience
Lin Z, Gao Z, Huang Y.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Culturally grounded health communication to support self-care among pregnant women with diabetes: Development and content validation of an educational cordel in Brazil. [PDF]

PLoS One
Gurgel FÉSL, da Silva RM, Gonçalves JL, do Nascimento CEM, de Abreu RNDC, Presado MHCV, Marie SKN.   +6 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Short-term factual recall, presence, and visio-vestibular discomfort in a 360° augmented-virtuality classroom environment: A feasibility study. [PDF]

PLoS One
Carrasco KD, Escarzaga AM, Gonzalez M, Rosenfelder A, Beltran N, Ford C, Miguel K, Scott LCA, Carrasco A.   +8 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source