Results 111 to 120 of about 76,054 (305)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Multispectral Imaging Sensors for Asteroids Relative Navigation [PDF]

, 2021
Current missions to asteroids largely rely on visible imaging to perform relative navigation with respect to the target surface. A consequence of observing the body in the visible band is the large influence of illumination conditions, which could be ...
Lavagna, M., Civardi, G. L., Quirino, M., Piccinin, M.   +3 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Analysis of Relative Motion of Collocated Geostationary Satellites with Geometric Constraints [PDF]

, 2013
This paper investigates the design of the relative motion orbits of geostationary satellites in the presence of geometric constraints. A geometric constraint is defined by a sensor's pointing direction and field of view.
de Bruijn, F.J., Gill, E.
core  

Absolute Navigation of High-Altitude and High-Speed Vehicles Using Relative Position Vector Measurements

Space: Science & Technology
Recent studies over the past few decades have indicated the utility of utilizing relative position vector information for the absolute navigation of carriers within the aerospace domain.
Xiucong Sun, Xiaoshuai Ma, Gengju Tian, Yukai Zhu, Shengzhou Bai, Haichao Gui   +5 more
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Vision-based pose estimation and relative navigation around uncooperative space objects [PDF]

, 2017
Autonomous relative navigation in space has been intensively studied in the last decades due to its vast range of applications. In particular, precise pose and motion estimation of an uncooperative object, such as a Resident Space Object (RSO) has a ...
Sarno, Salvatore, Lavagna Michelle, Pesce Vincenzo, Opromolla Roberto, Grassi Michele   +4 more
core  

Cooperative Navigation for Cross-Platform Dual-SINS Based on Relative Range and Angle Measurements

Sensors
In order to address the issue of rapidly divergent positioning errors of a single-platform inertial navigation system (INS) in GNSS-denied environments, this paper proposes a cross-platform cooperative navigation method based on relative range and angle ...
Jiang Lai, Shiqiao Qin, Xiangyuan Li, Jiaxing Zheng, Wenfeng Tan, Yingwei Zhao   +5 more
doaj   +1 more source