Results 41 to 50 of about 16,962 (222)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Formarea multistratificată a voinţei juridice a persoanei juridice de drept privat. Inaplicabilitatea, în principiu, a sancţiunii nulităţii contractelor încheiate cu nerespectarea regulilor de formare a voinţei juridice // The multi layered formation of the legal will of the private legal entity. The inapplicability, as a general rule, of the sanction of nullity to contracts concluded without adherence to the rules for the valid formation of the legal will

Analele Ştiinţifice ale Universităţii "Al.I. Cuza" din Iaşi. Ştiinţe Juridice
The legal will of the private law moral persons is structured and formed according to the same mechanism legally recognised for the natural person. The inner dimension of the legal will of moral persons is not a cognitive process, but the consequence of ...
Alin-Ioan Axente
doaj   +1 more source

Measurement-induced nonlocality over two-sided projective measurements

, 2012
Measurement-induced nonlocality (MiN), introduced by Luo and Fu [Phys. Rev. Lett. 106(2011)120401], is a kind of quantum correlation that beyond entanglement and even beyond quantum discord.
Guo Y., Li Z.-G., Nielsen M. A., YU GUO
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Contact co-isotropic CR submanifolds of a pseudo-Sasakian manifold

International Journal of Mathematics and Mathematical Sciences, 1984
It is proved that any co-isotropic submanifold M of a pseudo-Sasakian manifold M˜(U,ξ,η˜,g˜) is a CR submanifold (such submanfolds are called CICR submanifolds) with involutive vertical distribution ν1.
Vladislav V. Goldberg, Radu Rosca
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

THE LEGAL CONSEQUENCES OF THE CONSTITUTIONAL COURT’S DECISIONS IN THE CONTEXT OF THE LEGALITY PRINCIPLE OF THE CRIMINAL PROCEDURE [PDF]

Challenges of the Knowledge Society, 2019
The principle of legality of the criminal procedure is the established general rule according to which the criminal trial is carried out under the provisions stipulated by the law.
Liliana-Dorina RĂDUCU
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Sublating Kant and the Old Metaphysics: A Reading of the Transition from Being to Essence in Hegel's Logic [PDF]

, 1998
Kant’s “transcendental” or “critical” philosophy is an instance of what can be called the “critique of immediacy.” As part of his critical project, Kant argues that one cannot merely assume that there is a reestablished harmony between thought and being.
Baur, Michael
core   +1 more source