Results 51 to 60 of about 741 (249)
Societas et Iurisprudentia, 2014 The presented study focuses on the current issues of the factual employment. Its author specifically concentrates on the following key areas: legal definition of the factual employment; invalidity of the employment contract; foreign legal regulations ...
Helena Barancová
doaj
Codimension Two Homogeneous Sub-manifolds of Space Forms
, 2002 In this paper we study codimension two homogeneous submanifolds of Space Forms for which the index of minimum relative nullity is small. Such submanifolds have been studied in the case that they are immersed into the Euclidean space.
De Castro, Helvecio Pereira +1 more
core +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
, 2020 Avant l’ordonnance du 10 février 2016 portant droit des contrats, la majorité des études était basée sur la nullité prononcée par le juge, tandis que l’hypothèse d’une l’annulation voulue par les parties était confinée à une place subsidiaire, sinon à ...
Mevoungou Zambo, Romy Suzanne
core
, 2023 Given a Euclidean submanifold $\map{g}{M}{n}{\R^{n+p}}$, Chern and Kuiper provided inequalities between $\mu$ and $\nu_g$, the ranks of the nullity of $M^n$ and the relative nullity of $g$ respectively. Namely, they prove that $$\nu_g\leq\mu\leq\nu_g+p$$.
Guajardo, Diego
core
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source