Results 161 to 170 of about 9,629,773 (307)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
, 1958 "June 1958."; "Mission: To provide special emergency welfare services to individuals and families."A plan on serving the immediate needs of people in an enemy attack on the United ...
Kansas. Survival Plan Project.
core +1 more source
Five-year Relative Survival Rate of Skin Cancer in the USA, Europe and Japan [PDF]
Japanese Journal of Clinical Oncology, 2014 Megumi, Hori, Kota, Katanoda
openaire +2 more sources
Survival Analysis of Buccal Cancer and its Affecting Factors in a Medical Center of Central Taiwan
, 2009 [[abstract]]Background? Oral Cancer has been one of the top ten cancer diseases in Taiwan. It has become the fourth common cancer found especially in men. Moreover, the mortality rate of buccal cancer is rising higher yearly . Study objective?
FENG HEISH
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
The journal of the Japanese Practical Surgeon Society, 1983 NAITO, Kazuyo +6 more
openaire +2 more sources
Five-year Relative Survival Rate of Testis Cancer in the USA, Europe and Japan [PDF]
Japanese Journal of Clinical Oncology, 2014 Kota, Katanoda, Tomohiro, Matsuda
openaire +2 more sources
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Business Survival in Portuguese Regions [PDF]
This work addresses the post-entry performance of employer enterprises for seven regions in Portugal, at the NUT II level, by investigating the structural characteristics of survival, using non-parametric and semi-parametric methods, during the period ...
Alcina Nunes, Elsa de Morais Sarmento
core
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source