Results 121 to 130 of about 1,227,897 (305)
Free centre-by-nilpotent-by-abelian groups
, 2009 We prove that the free centre-by-(nilpotent-of-class-(c - 1))-by-abelian groups F/[γc(F′), F] are torsion-free for c = 6. This is in startling contrast to the cases when c is a prime and when c = 4, where these relatively free groups contain non-trivial ...
Johnson, Marianne +2 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
, 2021 Let V be a pseudovariety of finite groups such that free groups are residually V, and let ϕ: F(A) → F(B) be an injective morphism between finitely generated free groups.
Coulbois, Thierry +2 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Embeddings of relatively free groups into finitely presented groups
, 2000 We construct easy embeddings of relatively free groups (say the free Burnside group, the free solvable group) into finitely presented groups. We introduce a concept of verbal isoperimetric function of a group variety. We prove that if the verbal Dehn function of a relatively free group is bounded by a polynomial then the group can be embedded quasi ...
Olshanskii, A. Yu., Sapir, M. V.
openaire +2 more sources
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Accessibility Effects of a new Metro Line
FindingsThis study investigates how a new metro line currently being planned in the Oslo region will influence access to workplaces for the population. Geographically, the new line contributes to substantial accessibility gains in the immediate surroundings of ...
Erik Bjørnson Lunke +1 more
doaj +1 more source