Results 71 to 80 of about 13,952 (268)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On relatively normal spaces, relatively regular spaces, and on relative property (a)
Topology and its Applications, 1999 The following results concerning relative topological properties are proved: (1) A regular (Tychonoff) space \(Y\) is normal in every larger regular (Tychonoff) space if and only if \(Y\) is Lindelöf or normal almost compact. (2) A functionally Hausdorff space \(Y\) is regular in every larger functionally Hausdorff space if and only if \(Y\) is compact.
Matveev, M.V. +2 more
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Qom school and a critique of religious pluralism with special reference to Ayatollah Javadi Amoli's philosophical analysis [PDF]
Kom: Časopis za Religijske Nauke, 2019 In the past few decades, the school in the historic city of Qom has played an important role in directing strategic scientific and cultural developments in Iran and the Islamic world. Scientific and research work in this school has been going on for more
Halilović Seid
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Planck-Scale Soccer-Ball Problem: A Case of Mistaken Identity
Entropy, 2017 Over the last decade, it has been found that nonlinear laws of composition of momenta are predicted by some alternative approaches to “real” 4D quantum gravity, and by all formulations of dimensionally-reduced (3D) quantum gravity coupled to matter.
Giovanni Amelino-Camelia
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Relative and Pseudo-Relative Clauses in Slovene [PDF]
Slovene Linguistic Studies, 2007 The author explores the various types of relative clauses in Slovene, focusing on a construction that has traditionally been assumed to be a special type of relative clause in which there seems to be a mismatch between the number feature of the clitic pronoun and that of the relative head, e.g., Najboljši iskalec si, [RC kar smo jih imeli.]1 best-Nom ...
openaire +2 more sources