Results 151 to 160 of about 5,408,284 (306)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Shortening: The orthopedic theory of relativity

open access: yesJournal of Limb Lengthening & Reconstruction, 2020
Dror Paley
doaj   +1 more source

More on General Theory of Relativity vs. Special Theory of Relativity, Absolute Theory of Relativity, Parameterized Special Theory of Relativity, and NonInertial MultiRelativity

open access: yesHyperSoft Set Methods in Engineering
This paper continues and completes the analyses from paper [1]. The distinction between Special Relativity (SR) and General Relativity (GR) essentially boils down to whether gravity and acceleration are included in the math calculation. Also, distinctions between General Theory of Relativity vs.
openaire   +1 more source

Special theory of relativity

open access: yes, 1970
Special Theory of Relativity provides a discussion of the special theory of relativity. Special relativity is not, like other scientific theories, a statement about the matter that forms the physical world, but has the form of a condition that the ...
Kilmister, Clive William, ter Haar, D
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

The Meaning of Relativity Including the Relativistic Theory of the Non-Symmetric Field (Fifth Edition)

open access: yes, 1945
In 1921, five years after the appearance of his comprehensive paper on general relativity and twelve years before he left Europe permanently to join the Institute for Advanced Study, Albert Einstein visited Princeton University, where he delivered the ...
Greene, Brian, Einstein, Albert
core  

Realism and Relativity [PDF]

open access: yes, 2007
The line of argument pursued in this paper is to proceed from Einstein’s fundamental problem situation to a consideration of scientific representation with respect to the Special theory of relativity (STR). Einstein’s fundamental problem situation, which
Weinert, Friedel
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

A No-Go Theorem About Rotation in Relativity Theory [PDF]

open access: yes, 2000
Within the framework of general relativity, in some cases at least, it is a delicate and interesting question just what it means to say that an extended body is or is not "rotating". It is so for two reasons.
Malament, David B.
core  

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