Results 81 to 90 of about 5,408,284 (306)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Teaching general relativity theory in high school: why, what and how

open access: yesRevista de Enseñanza de la Física, 2017
In this work, which is part of a wider research, the problem of teaching the General Theory of Relativity in sec-ondary school is addressed, even though this theory is scarcely addressed even in physics degree courses.
Irene Arriassecq   +2 more
doaj  

Relative morsification theory

open access: yesTopology, 2004
In this paper we develope a Morsification Theory for holomorphic functions defining a singularity of finite codimension with respect to an ideal, which recovers most previously known Morsification results for non-isolated singulatities and generalize them to a much wider context.
openaire   +4 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Is the relativity principle consistent with electrodynamics? Towards a logico-empiricist reconstruction of a physical theory [PDF]

open access: yes, 2009
It is common in the literature on electrodynamics and relativity theory that the transformation rules for the basic electrodynamical quantities are derived from the hypothesis that the relativity principle (RP) applies for Maxwell's electrodynamics.
Gomori, Marton, Szabo, Laszlo E.
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Design, analysis and reformulation of a didactic sequence for teaching the special theory of relativity in high school

open access: yesRevista Brasileira de Ensino de Física
In this work, we design, implement and analyze a didactic sequence for the teaching of the basic topics of special relativity theory in high school. The sequence proposes a series of situations, specially designed to allow the emergence of the central ...
María Rita Otero   +2 more
doaj   +1 more source

Generalization of Clauses Relative to a Theory [PDF]

open access: yesMachine Learning, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Multifractality through Non-Markovian Stochastic Processes in the Scale Relativity Theory. Acute Arterial Occlusions as Scale Transitions. [PDF]

open access: yesEntropy (Basel), 2021
Tesloianu ND   +10 more
europepmc   +1 more source

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