Results 71 to 80 of about 19,218,504 (341)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

FINITE ELEMENT COMPUTATIONS OF TIME RELAXATION ALGORITHM FOR FLOW ENSEMBLES

open access: yesApplied Engineering Letters, 2016
Numerical continuous finite element computations of a fluid flow modelling based on ensemble technique are presented herein. This ensemble algorithm is based on time relaxation.
Monika Neda, Jiajia Waters
doaj  

Peculiarities of the process of switching polarization in polycrystalline thin films of lead zirconate-titanate [PDF]

open access: yesФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2018
The paper presents the results of a study of relaxation of the dielectric permittivities in constant electric fields upon switching the polarization of thin films of lead zirconate-titanate, crystallized at different annealing temperatures.
V.V. Ivanov   +5 more
doaj   +1 more source

Relaxation times of non-Markovian processes [PDF]

open access: yesPhysical Review A, 1987
We consider a general class of non-Markovian processes defined by stochastic differential equations with Ornstein-Uhlenbeck noise. We present a general formalism to evaluate relaxation times associated with correlation functions in the steady state. This formalism is a generalization of a previous approach for Markovian processes.
CASADEMUNT J   +4 more
openaire   +4 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Qualitative change in structural dynamics of some glass-forming systems

open access: yes, 2015
Analysis of temperature dependence of structural relaxation time in supercooled liquids revealed a qualitatively distinct feature - a sharp, cusp-like maxumum in the second derivative of its logarithm. It suggests that the super-Arrhenius behavior of the
Novikov, V. N., Sokolov, A. P.
core   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Molecular mobility in crystallising aromatic thermoplastic polyimide R-BAPS

open access: yesPhysics of Complex Systems, 2020
The molecular mobility of the thermoplastic aromatic R-BAPS polyimide films based on 1,3-bis (3,3’-4,4’-dicarboxyphenoxy) benzene (dianhydride) and 4,4’-bis (4-aminophenoxy) biphenyl was studied using the dielectric method.
Наталья Алексеевна Никонорова   +2 more
doaj   +1 more source

Internal friction caused by migration of the intercrystalline boundary in the metal

open access: yesФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2022
The model of internal friction at the migrating intercrystalline boundary is considered. Under the action of an alternating external stress oriented normally to the boundary, compression and stretching of the mating crystallites occurs.
V.G. Kul’kov, V.V. Kul’kova
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

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