Results 51 to 60 of about 1,181,754 (281)

Synthesis of α-hydroxy-β,β-difluoro-γ-ketoesters via [3,3]sigmatropic rearrangements [PDF]

open access: yes, 2000
Readily available γ,γ-difluorinated allylic alcohols obtained from trifluoroethanol were esterified efficiently. Exposure to strong base (LDA) afforded the ester enolates, in which chelation both controlled configuration and stabilised against ...
Broadhurst, Michael   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A novel calibration mechanism and the corresponding test bench for automotive clutch releasing fingers: Design, implementation, and verification

open access: yesAdvances in Mechanical Engineering, 2019
The clutch releasing finger acts as a disengagement lever and a clamping spring in the clutch, which remains in contact with the releasing bearing. Thus, the run-out of releasing fingers could result in vibrations of the clutch pedal and affect the ...
Zhengfeng Yan   +3 more
doaj   +1 more source

Releasing Earnings Distributions using Differential Privacy

open access: yesThe Journal of Privacy and Confidentiality, 2019
The U.S. Census Bureau recently released data on earnings percentiles of graduates from post-secondary institutions. This paper describes and evaluates the disclosure avoidance system developed for these statistics.
Andrew David Foote   +2 more
doaj   +1 more source

Design of millimeter-scale microwave-induced capsules and their non-instantaneous release

open access: yesMaterials & Design, 2023
In recent years, many studies have been carried out on the release system induced by the microwave signal, featured with great thermal efficiency and high penetration. However, studies on microwave responsive system on millimeter length scale are limited,
Haochuan Wang   +6 more
doaj   +1 more source

Differential Privacy of Aggregated DC Optimal Power Flow Data [PDF]

open access: yes, 2019
We consider the problem of privately releasing aggregated network statistics obtained from solving a DC optimal power flow (OPF) problem. It is shown that the mechanism that determines the noise distribution parameters are linked to the topology of the ...
Anderson, James   +2 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Gonadotropin releasing hormone agonists: Expanding vistas

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
Gonadotropin-releasing hormone (GnRH) agonists are derived from native GnRH by amino acid substitution which yields the agonist resistant to degradation and increases its half-life.
Navneet Magon
doaj   +1 more source

Research and Application of Open-Off Cut Roof Cutting Pressure Releasing Technology

open access: yesAdvances in Civil Engineering, 2021
The first weighting control is one of the difficult problems that cannot be avoided in the safe and efficient production of longwall mining face. To optimize the existing pressure releasing technology of open-off cut, the open-off cut roof cutting ...
Xingen Ma   +8 more
doaj   +1 more source

Differentially Private Release and Learning of Threshold Functions

open access: yes, 2015
We prove new upper and lower bounds on the sample complexity of $(\epsilon, \delta)$ differentially private algorithms for releasing approximate answers to threshold functions.
Bun, Mark   +3 more
core   +1 more source

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