Results 101 to 110 of about 2,934,024 (293)
Objectives: Endodontic instruments require thorough decontamination and sterilization before use and reuse to ensure the safety and success of treatments. However, standardized protocols are lacking.
Luigi Generali +6 more
doaj +1 more source
The aim of this study was to investigate the image retrieval from selected search engines according to the written and semantic features of Persian language and determine their relevance using recall and precision formulas and to identify the most ...
Yaghub Norouzi +2 more
doaj
One of the basic claims of relevance theory is that because a communicator asks for the attention of the addressee, the addressee is entitled to assume that the communicator is trying to be relevant, and interpret an utterance according to this ...
Groefsema, Marjolein
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Periodontitis is characterized by gingival regression, alveolar bone resorption and the development of deep periodontal pockets that, if left untreated, can lead to tooth loss. Currently, specific biomarkers are needed for the early, objective diagnosis,
Elisa Bellei +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
IntroductionPsoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory disease that negatively impacts patients’ quality of life. Patient-reported outcome measures (PROMs) are used to capture patient perspectives in disease assessment, and ...
Marika Lo Monaco +9 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Effect of Ozone on Adhesion of Bioactive Restorative Materials in Vitro
Objective: This in vitro preliminary study investigated how different ozone formulations affect the adhesion, surface topography, and interfacial ion release of two pediatric bioactive restorative materials. Materials and Methods: Standardized enamel and
Federica Veneri +6 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

