Results 91 to 100 of about 1,549,285 (265)

Measuring the relevance of retrieved images in search engines based on Persian language writing styles

Iranian Journal of Information Processing & Management, 2022
The aim of this study was to investigate the image retrieval from selected search engines according to the written and semantic features of Persian language and determine their relevance using recall and precision formulas and to identify the most ...
Yaghub Norouzi, Hoda Homavandi, Bent-ol hoda khabbazan   +2 more
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Proteomic Comparison between Periodontal Pocket Tissue and Other Oral Samples in Severe Periodontitis: The Meeting of Prospective Biomarkers

Sci
Periodontitis is characterized by gingival regression, alveolar bone resorption and the development of deep periodontal pockets that, if left untreated, can lead to tooth loss. Currently, specific biomarkers are needed for the early, objective diagnosis,
Elisa Bellei, Emanuela Monari, Carlo Bertoldi, Stefania Bergamini   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Critical importance of patient-reported outcomes for a comprehensive assessment of psoriatic arthritis patients

Frontiers in Medicine
IntroductionPsoriatic arthritis (PsA) is a heterogeneous, chronic inflammatory disease that negatively impacts patients’ quality of life. Patient-reported outcome measures (PROMs) are used to capture patient perspectives in disease assessment, and ...
Marika Lo Monaco, Marika Lo Monaco, Raffaella Mallaci Bocchio, Giuseppe Natoli, Annarita Giardina, Ignazio Cangemi, Salvatore Scibetta, Christiano Argano, Salvatore Corrao, Salvatore Corrao   +9 more
doaj   +1 more source

PESTOL - Framework for «Project Evaluation on Strategic, Tactical and Operational Levels»

International Journal of Information Systems and Project Management, 2022
The paper focuses on the development of the ex-post conceptual holistic framework for Project Evaluation on Strategic, Tactical and Operational Levels, the PESTOL model, by reviewing different definitions of project success and/or failure and combining ...
Youcef J-T. Zidane, Agnar Johansen, Bassam A. Hussein, Bjørn Andersen   +3 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Effect of Ozone on Adhesion of Bioactive Restorative Materials in Vitro

Acta Stomatologica Croatica
Objective: This in vitro preliminary study investigated how different ozone formulations affect the adhesion, surface topography, and interfacial ion release of two pediatric bioactive restorative materials. Materials and Methods: Standardized enamel and
Federica Veneri, Andrea Nobili, Giovanni Bolelli, Paolo Savadori, Tommaso Filippini, Ugo Consolo, Luigi Generali   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source