Results 81 to 90 of about 2,830,468 (238)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Dentistry JournalObjectives: Endodontic instruments require thorough decontamination and sterilization before use and reuse to ensure the safety and success of treatments. However, standardized protocols are lacking.
Luigi Generali +6 more
doaj +1 more source
Iranian Journal of Information Processing & Management, 2022 The aim of this study was to investigate the image retrieval from selected search engines according to the written and semantic features of Persian language and determine their relevance using recall and precision formulas and to identify the most ...
Yaghub Norouzi +2 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
SciPeriodontitis is characterized by gingival regression, alveolar bone resorption and the development of deep periodontal pockets that, if left untreated, can lead to tooth loss. Currently, specific biomarkers are needed for the early, objective diagnosis,
Elisa Bellei +3 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The Relevance of Science [PDF]
, 1974 The ultimate relevance of science is to try to discover man's purpose by every means in our ...
Porter, George
core
Effect of Ozone on Adhesion of Bioactive Restorative Materials in Vitro
Acta Stomatologica CroaticaObjective: This in vitro preliminary study investigated how different ozone formulations affect the adhesion, surface topography, and interfacial ion release of two pediatric bioactive restorative materials. Materials and Methods: Standardized enamel and
Federica Veneri +6 more
doaj +1 more source
PESTOL - Framework for «Project Evaluation on Strategic, Tactical and Operational Levels»
International Journal of Information Systems and Project Management, 2022 The paper focuses on the development of the ex-post conceptual holistic framework for Project Evaluation on Strategic, Tactical and Operational Levels, the PESTOL model, by reviewing different definitions of project success and/or failure and combining ...
Youcef J-T. Zidane +3 more
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source