Results 61 to 70 of about 2,830,468 (238)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Dentistry JournalObjectives: Potential adverse effects and pH-related effectiveness of bleaching agents have raised some concerns. The aim of this study was to compare three bleaching agents containing hydrogen peroxide (HP) and carbamide peroxide (CP) in terms of ...
Federica Veneri +6 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Relevance Criteria Used by Teachers in Selecting Oral History Materials [PDF]
, 2005 From a user-centered and task-specific perspective on relevance, we studied the relevance criteria used by teachers - an understudied but important group - who were searching for materials to use in the classroom to support learning on a particular theme.
Lawley, Katy Newton +2 more
core +1 more source
VASIL SUKHOMLYNSKY’S SCHOOL AS AN AUTHOR’S PEDAGOGICAL SYSTEM
Education: Modern Discourses, 2018 The article presents the essential features of V. Sukhomlynsky’s school as an autho’s pedagogical system on the basis of holistic analysis. It is proved that the pedagogical system of the outstanding teacher in its essence and character belongs to ...
Anna Trotsko, Olena Popova
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Practice Exam (Maths and Physics Relevance)
, 2016 An engineering student encounters strange circumstances while practicing for her maths exam. A fictional film highlighting the relevance of first year mathematical concepts. It was produced by Swinburne engineering and multimedia students.
José Sánchez +8 more
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Frontiers in ImmunologyBiologic and targeted synthetic disease-modifying antirheumatic drugs (DMARDs) have transformed the management of chronic inflammatory diseases. Yet their therapeutic impact extends beyond cytokine suppression, influencing systemic metabolic pathways ...
Salvatore Corrao +9 more
doaj +1 more source