Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Spatial statistical learning of task relevance, rather than stimulus prevalence, improves visual working memory recall. [PDF]
Xu L +4 more
europepmc +1 more source
Future drought over Urmia Lake Basin under SSP scenarios: the relevance of snow melt
Maral Habibi +2 more
openalex +1 more source
Zachos, F.E. 2016. Species Concepts in Biology. Historical Development, Theoretical Foundations and Practical Relevance. Springer International Publishing Switzerland, [place not stated]. xii+220 pp. ISBN 978-3-319-44964-7. [PDF]
Alessandro Minelli
openalex +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Not just heard, but judged: a multidimensional perspective on auditory attention in everyday life. [PDF]
Korte S, Bleichner MG.
europepmc +1 more source
Team Decision Making in the Emergency Units: Exploring the Relevance of Checklists and Expertise
Karen Ranestad
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Relevance of stress coping management to prophet Muhammad SAW’s tradition (study Kutub al-Tis‘ah) [PDF]
Aufal Khima
openalex
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source

