Results 221 to 230 of about 5,221,373 (330)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Correction: Nassar et al. Sol-Gel-Synthesized Metal Oxide Nanostructures: Advancements and Prospects for Spintronic Applications-A Comprehensive Review. <i>Gels</i> 2025, <i>11</i>, 657. [PDF]

Gels
Nassar KI, Teixeira SS, Graça MPF.
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Photodynamic Inactivation Mediated by Endogenous Porphyrins of Corynebacterium diphtheriae in Planktonic and Biofilm Forms

ACS Omega
Gabriela Batista Alves, Mônica Regina da Costa Marques Calderari, Eduardo Nunes da Fonseca, Lincoln de Oliveira Sant’anna, Louisy Sanches dos Santos, Ana Luiza de Mattos-Guaraldi   +5 more
doaj   +1 more source

Student perspectives on integrating basic and clinical dental sciences: insights from three dental schools in Norway. [PDF]

Front Dent Med
Kristensen AT, Thune NH, Khan Q, Utheim TP, Hammer HL, Sehic A.   +5 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Identifying key outcome domains with underlying specific patient-reported outcomes for psychomotor therapy in mental health care in the Netherlands: a multi-phased qualitative study. [PDF]

Qual Life Res
de Haan A, Moeijes J, Scheffers M, van der Wees P.   +3 more
europepmc   +1 more source

The Promises of Freedom: The Contemporary Relevance of the Thirteenth Amendment

, 2013
William M. Carter
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Publishing Relevant Health Research. [PDF]

Acta Med Philipp
Sison-Aguilar AG.
europepmc   +1 more source