Results 71 to 80 of about 2,027,234 (292)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
L’image à l’épreuve de l’ironie
How to decide when a filmmaker effectively diplays an ironic image, i.e, according to Sperber & Wilson, an act of language which « attracts more attention on the utterance itself than on what the utterance is about » ?
Laurent Jullier
doaj +1 more source
Towards a relevance-theoretic approach to the diminutive morpheme
This paper intends to lay the foundations for a relevance-theoretic approach to the diminutive morpheme. In many languages, this morpheme is attached to nouns, adjectives, adverbs or verbs.
Manuel Padilla Cruz
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Flexibility, Dissonance and the conscious consumer [PDF]
This paper considers the ethical purchasing of what are described as conscious consumers. Conscious consumers present a complex mix of behaviors; while seeking ethical alternatives, other social and economic forces impact on their behavior such that ...
Carrigan, Marylyn +2 more
core
Cosmological perturbation theory
This is a review on cosmological perturbation theory. After an introduction, it presents the problem of gauge transformation. Gauge invariant variables are introduced and the Einstein and conservation equations are written in terms of these variables ...
R. Durrer, T. Kanazawa, V. F. Mukhanov
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The SU(3) bosons and the spin nematic state on the spin-1 bilinear-biquadratic triangular lattice
A bond-operator mean-field theory in the SU(3) bosons representation is developed to describe the antiferro-nematic phase of the spin-1 bilinear-biquadratic model. The calculated static structure factors reveal delicately that the antiferro-nematic state
A. Auerbach +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

