Results 71 to 80 of about 239,051 (251)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Biblical Performance Criticism: Survey and Prospects
Religions, 2019 Biblical Performance Criticism (BPC) analyzes communication events of biblical traditions for audiences. Every communication event of a tradition has four aspects: a communicator, traditions re-expressed, an audience, and a social situation.
Peter S. Perry
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Bible translation and relevance theory [PDF]
Stellenbosch Papers in Linguistics Plus, 2014 No abstract available.
openaire +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Argumentation and Cognition: Can Pragma-Dialectics Interplay with Pragma-Semantics?
Critical Approaches to Discourse Analysis across Disciplines, 2007 This paper addresses the possibility of a cognitive account of argumentation, by focusing on a tentative interplay between one of today’s most influential theories of argumentation – van Eemeren and Grootendorst’s Pragma-Dialectics – and Relevance Theory.
Steve Oswald
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Towards a pragmatics of non-fictional narrative truth: Gricean and relevance-theoretic perspectives
Stellenbosch Papers in Linguistics Plus, 2016 From a linguistic perspective, ‘truth’ is undoubtedly a pragmatic notion, as the truth of an utterance is not determined solely by its linguistic meaning, but is dependent upon the context in which it is uttered.
Berghoff, Robyn, Huddlestone, Kate
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Completeness of relevant quantification theories.
Notre Dame Journal of Formal Logic, 1974 In [20], Meyer and Dunn answered affirmatively for the relevant sentential logics E and R the question, "Is the rule y, 'From v-A and f-Av5, to infer B,' admissible?" This result, which confirmed an old conjecture of Anderson and Belnap, establishes the weak completeness of these and a number of related logics.
Meyer, Robert K. +2 more
openaire +4 more sources