Results 101 to 110 of about 1,241,577 (251)

Sensitivity analysis of reliability constrained, eco optimal solar, wind, hydrogen storage based islanded power system

Scientific Reports
The global energy expansion strategy has incorporated islanded renewable energy-based power generation systems to electrify remote communities. The development of these renewable energy systems (RES) decreases grid dependency and operational costs. Solar
Nishant Thakkar, Priyanka Paliwal, Deepa Kaliyaperumal, V. Ravikumar Pandi, Narayan Prasad Gupta, Marco Merlo   +5 more
doaj   +1 more source

Reliability of information systems in organization in the context of banking sector: Empirical study from Poland

Cogent Business & Management, 2018
The notion of information systems (IS) reliability in organization is discussed in this article. It contains critical review of the literature, definition of IS reliability and brief overview of the theoretical model of IS reliability in organization ...
Katarzyna Tworek
doaj   +1 more source

A sensitivity analysis for the adequacy assessment of a multi-state physics modeling approach for reliability analysis [PDF]

, 2016
In this work, a moment-independent Sensitivity Analysis (SA) based on Hellinger distance and Kullback-Leibler divergence is proposed to identify the component of a system most affecting its reliability (Diaconis et al., 1982; Gibbs et al., 2002; Di Maio ...
di Maio, F., Wang, W., Zio, E.
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Dynamic Reliability Analysis of RV Reducer Considering Strength Degradation and Dependent Failure

Jixie chuandong, 2020
The strength degradation and dependent failure， which have not been taken into account yet in the existing RV reducer reliability analysis methods， have a significant impact on the reliability of mechanical systems.
Du Xuesong, Lou Jiabin, Huang Yucheng, Liu Hao   +3 more
doaj  

An adaptive sampling method for global sensitivity analysis based on least-squares support vector regression [PDF]

, 2018
In the field of engineering, surrogate models are commonly used for approximating the behavior of a physical phenomenon in order to reduce the computational costs.
Bourinet, Jean-Marc, Lahmer, Tom (Prof.), Steiner, Maria (M.Sc.)   +2 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Reliability-Based Sensitivity Analysis of the Dynamic Response of Railway Bridges

, 2022
In response to the planned increase in operational speeds and axle loads of passengertrains that may lead to resonance-induced excessive vibrations in railway bridges,recent studies examined the reliability of bridges concerning train running safety andpassenger comfort limit states.
openaire   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source