Results 61 to 70 of about 1,241,577 (251)

The Positive Thinking Skills Scale: A Screening Measure for Early Identification of Depressive Thoughts [PDF]

open access: yes, 2017
Background Depression is currently considered the second leading cause of disability worldwide. Positive thinking is a cognitive process that helps individuals to deal with problems more effectively, and has been suggested as a useful strategy for coping
Bekhet, Abir K.   +1 more
core   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Testing and comparing two self-care-related instruments among older Chinese adults [PDF]

open access: yes, 2017
Objectives The study aimed to test and compare the reliability and validity, including sensitivity and specificity of the two self-care-related instruments, the Self-care Ability Scale for the Elderly (SASE), and the Appraisal of Self-care Agency Scale ...
A Millar   +50 more
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Temperature and Polarization CMB Maps from Primordial non-Gaussianities of the Local Type

open access: yes, 2007
The forthcoming Planck experiment will provide high sensitivity polarization measurements that will allow us to further tighten the f_NL bounds from the temperature data.
Hansen, Frode K.   +5 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

NUMERICAL SIMULATION AND RELIABILITY SENSITIVITY ANALYSIS OF BIONIC KILLER WHALES’S LOAD CHARACTERISTIC

open access: yesJixie qiangdu, 2021
As a kind of bionic robot fish,bionic killer whale played an important role in ocean development and scientific investigation. Based on the flapping wing movement theory,the bionic killer whale’s mechanism was analyzed,its instantaneous load was ...
LI MingHao   +5 more
doaj  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Reliability sensitivity analysis using axis orthogonal importance Latin hypercube sampling method

open access: yesAdvances in Mechanical Engineering, 2019
In this article, a combined use of Latin hypercube sampling and axis orthogonal importance sampling, as an efficient and applicable tool for reliability analysis with limited number of samples, is explored for sensitivity estimation of the failure ...
Wei Zhao, YangYang Chen, Jike Liu
doaj   +1 more source

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