Results 61 to 70 of about 1,254,315 (297)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Testing and comparing two self-care-related instruments among older Chinese adults [PDF]

, 2017
Objectives The study aimed to test and compare the reliability and validity, including sensitivity and specificity of the two self-care-related instruments, the Self-care Ability Scale for the Elderly (SASE), and the Appraisal of Self-care Agency Scale ...
A Millar, AL Comfrey, BF Damásio, BY Kearney, CL Wong, D. L. Streiner, Daniel Serrani Azcurra, DE Orem, EJ Pedhazur, GC Evers, GX Zeng, H Gao, H Gao, Han Gao, HH Wang, JA Zauszniewski, Jacqueline McCallum, JC Nunally, JW Osborne, JZ Shi, K Sundsli, Kun Liu, L Guo, L Guo, L Robinson, Lina Guo, LN Guo, M Lorensen, M Lorensen, M Zhou, MH Almeida, MS Fok, O Söderhamn, O Söderhamn, O Söderhamn, O Söderhamn, O Söderhamn, Qiyun Guo, RW Brislin, ST Tomstad, ST Tomstad, T van Achterberg, Ulrika Söderhamn, VD Sousa, X Wang, X Wang, XG Wang, Xianfei Ding, Yanjin Liu, YL Gao, ZS Nasreddine   +50 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

NON-PROBABILISTIC RELIABILITY SENSITIVITY ANALYSIS BASED ON CONVEX MODEL

Jixie qiangdu, 2019
Reliability sensitivity determines the relationship between reliability and the distribution parameters of uncertain variables, and guides reliability analysis and reliability design.
QIAO XinZhou, SU QuanWei, LI Long, Ge HongYu   +3 more
doaj  

A reliability-based robust design for structural components with a variable cross section under limited probabilistic information

Advances in Mechanical Engineering, 2017
In engineering design, structural components with variable cross sections are extensively employed due to their excellent mechanical properties. From a strength and stiffness perspective, structural components with a uniform cross section are not always ...
Tianxiao Zhang, David He
doaj   +1 more source

Global sensitivity analysis of computer models with functional inputs [PDF]

, 2007
Global sensitivity analysis is used to quantify the influence of uncertain input parameters on the response variability of a numerical model. The common quantitative methods are applicable to computer codes with scalar input variables. This paper aims to
Iooss, Bertrand, Ribatet, Mathieu
core   +6 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Reliability models of belt drive systems under slipping failure mode

Advances in Mechanical Engineering, 2017
Conventional reliability assessment and reliability-based optimal design of belt drive are based on the stress–strength interference model. However, the stress–strength interference model is essentially a static model, and the sensitivity analysis of ...
Peng Gao, Liyang Xie
doaj   +1 more source

Decoding herbal materials of TCM preparations with the multi-barcode sequencing approach

Scientific Reports, 2022
With the rapid development of high-throughput sequencing technology, approaches for assessing biological ingredients in Traditional Chinese Medicine (TCM) preparations have also advanced.
Qi Yao, Xue Zhu, Maozhen Han, Chaoyun Chen, Wei Li, Hong Bai, Kang Ning   +6 more
doaj   +1 more source

Quantification of Model Uncertainty Based on Variance and Entropy of Bernoulli Distribution

Mathematics, 2022
This article studies the role of model uncertainties in sensitivity and probability analysis of reliability. The measure of reliability is failure probability.
Zdeněk Kala
doaj   +1 more source