Results 111 to 120 of about 24,260,019 (288)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Graph Neural Networks for Evaluating the Reliability and Resilience of Infrastructure Systems: A Systematic Review of Models, Applications, and Future Directions

IEEE Access
Interdependent infrastructure systems serve as the foundation of modern society, ensuring the delivery of essential services, economic stability, and public well-being. The increasing integration of these systems, driven by advancements in cyber-physical
Tong Liu, Fangyu Liu
doaj   +1 more source

Bayesian zero-failure reliability demonstration [PDF]

, 2005
We study required numbers of tasks to be tested for a technical system, including systems with built-in redundancy, in order to demonstrate its reliability with regard to its use in a process after testing, where the system has to function for different ...
Rahrouh, Maha
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Reliability Analysis of Deep Foundation Pit Using the Gaussian Copula-Based Bayesian Network

Mathematics
Urban underground space development has heightened concerns over the safety of deep foundation pit construction. This study conducted time-series monitoring of critical safety-influencing factors and applied the Gaussian copula-based Bayesian network ...
Bin Tan, Qiyuan Peng
doaj   +1 more source

An improved Cox proportional hazards model for reliability analysis of aviation gas turbines considering varying environmental conditions and operational settings

Aviation gas turbines are critical components in the aerospace industry, where reliability directly influences maintenance costs, operational efficiency, and safety.
Cui, Bo
core  

Electronic parts reliability data 1997

, 1996
This document contains reliability data on both commercial and military electronic components for use in reliability analyses. It contains failure rate data on integrated circuits, discrete semiconductors (diodes, transistors, optoelectronic devices ...
Jaworski, Paul, Mahar, David, Denson, William, Crowell, William   +3 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source