Results 91 to 100 of about 4,030,856 (299)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Stability of heterogeneous linear and nonlinear car-following models

Franklin Open
Stop-and-go waves in congested road traffic are complex collective phenomena with significant implications for traffic engineering, road safety and the environment.
Matthias Ehrhardt, Antoine Tordeux
doaj   +1 more source

Reliability estimation in interaction analysis

Communication Quarterly, 1984
Interaction analysts use a variety of nominal, ordinal, and interval level tests to assess coding reliability. This paper evaluates approaches to measuring reliability in interaction analysis by: (1) presenting criteria for a sound reliability estimate, (2) evaluating currently used tests against these criteria, and (3) discussing application of ...
Weider-Hatfield, D., Hatfield, J.D.
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A comparative reliability analysis of ETCS train radio communications [PDF]

, 2005
StoCharts have been proposed as a UML statechart extension for performance and dependability evaluation, and were applied in the context of train radio reliability assessment to show the principal tractability of realistic cases with this approach.
Hermanns, H., Jansen, D.N., Usenko, Y.S.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Some Reliability Issues of the Corrugated I-Beam Girder

Engineering Transactions, 2015
The main aim of this paper is reliability analysis of the corrugated-web I-girder carried out to verify its susceptibility to the random corrosion of the web and to make a comparison of the results of the first and of the second order reliability ...
Damian SOKOŁOWSKI, Marcin Marek KAMIŃSKI   +1 more
doaj   +1 more source

Metamodel-based importance sampling for structural reliability analysis

, 2011
Structural reliability methods aim at computing the probability of failure of systems with respect to some prescribed performance functions. In modern engineering such functions usually resort to running an expensive-to-evaluate computational model (e.g.
Deheeger, F., Dubourg, V., Sudret, B.
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Damage of additively manufactured polymer materials: experimental and probabilistic analysis

Fracture and Structural Integrity
This paper presents a study on the tensile, fracture, damage, and reliability properties of 3D printed polylactic acid (PLA), based on a series of experiments. The study focuses on polylactic acid (PLA) samples produced using fused filament manufacturing
Hachimi Taoufik, Ait Hmazi Fouad, Majid Fatima   +2 more
doaj   +1 more source