Results 71 to 80 of about 24,260,019 (288)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Mission Planning for UAV Swarm with Aircraft Carrier Delivery: A Decoupled Framework
Due to the limited endurance of UAVs, especially in scenarios involving large areas and dense target nodes, it is challenging for multiple UAVs to complete diverse tasks while ensuring timely execution.
Hongyun Zhang +7 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Numerical Permeation Models to Predict the Annulus Composition of Flexible Pipes
The migration of acid gases through the pressure sheath of flexible pipes may induce a corrosive environment that can lead to steel armors’ failure by SCC (stress corrosion cracking).
João Marcos B. Vieira +1 more
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Development of fifth‐generation technology leads to a growing demand for materials with exceptional thermal property, mechanical strength, and low dielectric loss. However, ensuring the broad application of such materials by comprehensively investigating
Peijiang Liu +9 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
This study delves into the challenge of efficiently digitalising wind turbine maintenance data, traditionally hindered by non‐standardised formats necessitating manual, expert intervention. Highlighting the discrepancies in past reliability studies based
Julia Walgern +6 more
doaj +1 more source
Fatigue Reliability Optimization for Three-Axle Bogie Frame Based on Response Surface Method
The three-axle bogie frame was taken as the research object, the reliability analysis for structural strength and fatigue life of the key welds were carried out.
Xinli HAN, Yuehua GAO
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source

