Results 31 to 40 of about 1,258,106 (256)

Developing Sustainable Life Support System Concepts [PDF]

open access: yes, 2010
Sustainable spacecraft life support concepts may allow the development of more reliable technologies for long duration space missions. Currently, life support technologies at different levels of development are not well evaluated against each other, and ...
Thomas, Evan A.
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Capacitor failure rate determination test Quarterly progress report, period ending Dec. 1965 [PDF]

open access: yes
Life testing and reliability engineering of film-foil polycarbonate capacitors for static convertors and ...
Dysart, W. C.
core   +1 more source

Psychometric Evaluation of the Physical Activity Enjoyment Scale in Adults with Functional Limitations [PDF]

open access: yes, 2016
Enjoyment is an important construct for understanding physical activity participation, and it has not been examined in adults with functional limitations.
Bekhet, Abir K.   +2 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Four-point bending cycling : the alternative for thermal cycling solder fatigue testing of electronic components [PDF]

open access: yes, 2017
This paper deals with an alternative testing approach for quantifying the life time of board level solder joint reliability of components. This approach consists of applying a relative shear displacement between component and Printed Circuit Board (PCB ...
Allaert, Bart   +9 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Effectiveness of spacecraft testing programs [PDF]

open access: yes
The need for testing under simulated mission operational conditions is discussed and the results of such tests are reviewed from the point of view of the user.
Krausz, A.
core   +1 more source

Fatigue Reliability Analysis of Wind Turbine Cast Components [PDF]

open access: yes, 2017
The fatigue life of wind turbine cast components, such as the main shaft in a drivetrain, is generally determined by defects from the casting process.
Fæster, Søren   +3 more
core   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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