Results 41 to 50 of about 287,831 (260)

Validation and Reliability of Indonesian Version of Vitiligo-Specific Health-Related Quality of Life Instrument (VITIQoL)

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2023
Background: Vitiligo is a long-term autoimmune disorder marked by the loss of melanocytes and the formation of white macules. Vitiligo can have an impact on the patient's look and quality of life.
Diah Mira Indramaya, Aprilin Krista Devi, Sawitri, Budi Utomo, Izzatul Fithriyah, Dwi Murtiastutik, Afif Nurul Hidayati   +6 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

An Estimation of the Entropy for a Double Exponential Distribution Based on Multiply Type-II Censored Samples

Entropy, 2012
In many life-testing and reliability studies, the experimenter might not always obtain complete information on failure times for all experimental units. Multiply Type-II censored sampling arises in a life-testing experiment whenever the experimenter does
Jun-Tae Han, Jinsoo Kim, Suk-Bok Kang, Young-Seuk Cho   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Reliability evaluation method and system for the ventilation door cylinder based on Bayes Monte Carlo simulation

Scientific Reports
The automatic ventilation door in mining operations is a crucial component for ensuring production safety and maintaining ventilation system stability.
Peiyang Su, Liwen Guo, Jiayong Zhang, Li Ma   +3 more
doaj   +1 more source

Acceleration of Service Life Testing by Using Weibull Distribution on Fiber Optical Connectors

Applied Sciences
The service life assessment of previous fatigue stress has a fundamental role in estimating the reliability of products like fiber optical connectors, and should replicate use in severe environments in telecommunications systems.
Jesús M. Barraza-Contreras, Manuel R. Piña-Monarrez, María M. Hernández-Ramos, Osvaldo Monclova-Quintana, Secundino Ramos-Lozano   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Design of Control Chart in Presence of Hybrid Censoring Scheme

IEEE Access, 2018
In this paper, a new reliability testing control chart has been developed using the hybrid censoring scheme for the Weibull distribution. The in-control and out-of-control probabilities are estimated for the desired quality characteristic using the ...
Muhammad Aslam, Ritwik Bhattacharya, Mansour Sattam Aldosari   +2 more
doaj   +1 more source

Modular System Modeling for Quantitative Reliability Evaluation of Technical Systems [PDF]

Modeling, Identification and Control, 2016
In modern times, it is necessary to offer reliable products to match the statutory directives concerning product liability and the high expectations of customers for durable devices. Furthermore, to maintain a high competitiveness, engineers need to know
Stephan Neumann, L. Woell, Achim Feldermann, Felix Strassburger, Georg Jacobs   +4 more
doaj   +1 more source