Results 61 to 70 of about 854,672 (266)

On Reliability of Patch Correctness Assessment

2019 IEEE/ACM 41st International Conference on Software Engineering (ICSE), 2019
Current state-of-the-art automatic software repair (ASR) techniques rely heavily on incomplete specifications, or test suites, to generate repairs. This, however, may cause ASR tools to generate repairs that are incorrect and hard to generalize.
Xuan-Bach Dinh Le 0001, Lingfeng Bao, David Lo 0001, Xin Xia 0001, Shanping Li, Corina S. Pasareanu   +5 more
openaire   +3 more sources

Reliability of the Deployment Resiliency Assessment [PDF]

Military Medicine, 2016
This article describes the reliability of the instruments embedded in a mental health screening instrument designed to detect risky drinking, depression, and post-traumatic stress disorder among members of the Armed Forces. The instruments were generally reliable, however, the risky drinking screen (Alcohol Use Disorders Identification Test-Consumption)
Samuel E, Simon, Kate, Stewart, Michelle, Kloc, Thomas V, Williams, Margaret C, Wilmoth   +4 more
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Matrix-Based Analytical Approach for Reliability Assessment of Mesh Distribution Networks

Energies
To address the limitations of conventional reliability assessment methods in handling mesh distribution networks with flexible operation characteristics and complex topologies, namely their poor adaptability and low computational efficiency, this paper ...
Shuitian Li, Lixiang Lin, Ya Chen, Chang Xu, Chenxi Zhang, Yuanliang Zhang, Fengzhang Luo, Jiacheng Fo   +7 more
doaj   +1 more source

Hot Spot Temperature and Grey Target Theory-Based Dynamic Modelling for Reliability Assessment of Transformer Oil-Paper Insulation Systems: A Practical Case Study

Energies, 2018
This paper develops a novel dynamic correction method for the reliability assessment of large oil-immersed power transformers. First, with the transformer oil-paper insulation system (TOPIS) as the target of evaluation and the winding hot spot ...
Lefeng Cheng, Tao Yu, Guoping Wang, Bo Yang, Lv Zhou   +4 more
doaj   +1 more source

Reliability assessment of wind turbines

, 2013
Wind turbines can be considered as structures that are in between civil engineering structures and machines since they consist of structural components and many electrical and machine components together with a control system. Further, a wind turbine is not a one-of-a-kind structure but manufactured in series production based on many component tests ...
openaire   +4 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Osprey Optimization Algorithm-Optimized Kriging-RBF Method for Radial Deformation Reliability Analysis of Compressor Blade Angle Crack

Aerospace
Angle crack defects significantly affect compressor blade radial deformation characteristics, posing critical challenges for reliability assessment under operational uncertainties. This study proposes a novel osprey optimization algorithm (OOA)-optimized
Qiong Zhang, Shuguang Zhang, Xuyan He
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source