Results 81 to 90 of about 1,364,177 (309)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
The analysis of reliability of pedagogical test of a course of mathematics on the subject "Ranks"
Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2017 This work is devoted to the analysis of quality of pedagogical dough on the subject "Ranks" of a course of mathematics which is applied to check of level of knowledge of students at the first year of SAMGTU.
Ludmila V. Limanova
doaj
The Logical Structure of Cronbach's Coefficient Alpha, and its Precision in Estimating Reliability under Measurement Models Assumptions. [PDF]
Journal of Islamic Studies, 2009 The study examined three main research questions: 1- What is the logical structure of Cronbach's Coefficient Alpha and its implications" 2- Under what measurement models and cicumstances the use of Coefficient Alpha produce either accurate or biased ...
Mohamed Tighezza
doaj
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2016 One of ways of control of knowledge is testing of pupils. The purpose of this work is improvement of quality of pedagogical dough on the subject "Integral calculus" of a course of the higher mathematics which is applied to an assessment of knowledge of ...
Larisa V. Limanova
doaj
Chinese version and reliability and validity test of the Cancer Support Person's Unmet Needs Survey
Huli yanjiu, 2022 ObjectiveTo translate the Cancer Support Person's Unmet Needs Survey（SPUNS⁃SF23），and to test its reliability and validity.MethodsChinese version of SPUNS⁃SF23 was formed by translation and cultural adjustment.A total of 280 family caregivers of renal ...
LI Dongdong, CHEN Qingli, SUN Ting
doaj
Don’t Forget the Model in Your Model-based Reliability Coefficients: A Reply to McNeish (2018)
Collabra: Psychology, 2019 McNeish (2018) advocates that researchers abandon coefficient alpha in favor of alternative reliability measures, such as the 1-factor reliability (coefficient omega), a total reliability coefficient based on an exploratory bifactor solution (“Revelle’s ...
Victoria Savalei, Steven P. Reise
doaj +1 more source
Intra- and inter-examiner Reliability of Direct Facial Soft Tissue Measurements Using Digital Calipers [PDF]
, 2012 Background: The objective of this study is to determine if facial soft tissue measurements using digital calipers can be reliably taken by the same examiner and by a large group of examiners. Materials and Methods: Ten examiners performed a set of 18 in-
Bosio, Jose A. +3 more
core +2 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source