Results 61 to 70 of about 438,848 (266)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

A New Reliability Coefficient Using Betting Commitment Evidence Distance in Dempster-Shafer Evidence Theory for Uncertain Information Fusion. [PDF]

Entropy (Basel), 2023
Tang Y, Wu S, Zhou Y, Huang Y, Zhou D.
europepmc   +1 more source

Exponential Reliability Coefficient based Reputation Mechanism for isolating selfish nodes in MANETs

Egyptian Informatics Journal, 2015
In mobile ad hoc networks, cooperation among active mobile nodes is considered to play a vital role in reliable transmission of data. But, the selfish mobile nodes present in an ad hoc environment refuse to forward neighbouring nodes’ packet for ...
J. Sengathir, R. Manoharan
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Usos del coeficiente alfa de Cronbach en el análisis de instrumentos escritos The usage of the Cronbach Coefficient alpha in the Analysis of the Written Instruments

Revista Médica Electrónica, 2012
Se realizó un estudio de carácter evaluativo para determinar la precisión de un examen escrito mediante un análisis de fiabilidad. El examen, integrado por 30 preguntas que exploran cierto tipo de conocimiento profesional, se aplicó a 45 personas, y con ...
Silvio Faustino Soler Cárdenas, Lisbet Soler Pons   +1 more
doaj  

Ballou’s Ancestral Inbreeding Coefficient: Formulation and New Estimate with Higher Reliability

Animals
Inbreeding is unavoidable in small populations. However, the deleterious effects of inbreeding on fitness-related traits (inbreeding depression) may not be an inevitable phenomenon, since deleterious recessive alleles causing inbreeding depression might ...
Tetsuro Nomura
doaj   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Measurement Reliability in Psychology: Method Development, Infatuation with Cronbach’s Alpha Coefficient, and Recommendations for Appropriate Reliability Estimation

Psychological Topics, 2020
The purpose of this review article is to indicate the abundant history of the concept of measurement reliability and steep improvement in reliability estimation since the 1940s, which produced a large number of approaches to its estimation.
Josip Novak
doaj  

Guideline for Selecting Types of Reliability and Suitable Intra-class Correlation Coefficients in Clinical Research

Journal of Biostatistics and Epidemiology, 2021
Introduction: Reliability is an integral part of measuring the reproducibility of research information. Intra-cluster correlation coefficient (ICC) is one of the necessary indicators for reliability reporting, which can be misleading in terms of its ...
Khalil Taherzadeh Chenani, Farzan Madadizadeh   +1 more
doaj