Results 41 to 50 of about 442,003 (266)

Assessing Reliability of a Multi-Dimensional Scale by Coefficient Alpha [PDF]

Revija za Elementarno Izobraževanje, 2016
The purpose of the study was to assess internal consistency by calculating coefficient alpha. It presents the variation in coefficient alpha, depending on questionnaire length and the homogeneity or heterogeneity of the questionnaire.
Ivan Šerbetar, Iva Sedlar
doaj  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Reliability and validity of free software for the analysis of locomotor activity in mice [PDF]

Yeungnam University Journal of Medicine, 2018
Background Kinovea software that tracking semi-automatically the motion in video screen has been used to study motion-related tasks in several studies. However, the validation of this software in open field test to assess locomotor activity have not been
Yoo Rha Hong, Eunsoo Moon
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The analysis of reliability of pedagogical test of a course of mathematics on the subject "Ranks"

Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2017
This work is devoted to the analysis of quality of pedagogical dough on the subject "Ranks" of a course of mathematics which is applied to check of level of knowledge of students at the first year of SAMGTU.
Ludmila V. Limanova
doaj  

Generalized Reliability Coefficients for Complex Surveys with Unit Nonresponse

Mathematics
Regarding the reliability that explains a construct formed by a weighted sum of multiple variables, this study employs a nonmodel-based approach independent of factor models.
Hyeonah Park, Seongryong Na
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Improvement of quality of pedagogical dough from a course of the higher mathematics on a subject "integral calculus"

Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2016
One of ways of control of knowledge is testing of pupils. The purpose of this work is improvement of quality of pedagogical dough on the subject "Integral calculus" of a course of the higher mathematics which is applied to an assessment of knowledge of ...
Larisa V. Limanova
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source