Results 41 to 50 of about 1,364,177 (309)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Reliability-based analysis of recycled aggregate concrete under carbonation [PDF]

open access: yes, 2018
Durability represents a crucial issue for evaluating safety and serviceability of reinforced concrete structures. Many studies have already focused on carbonation-induced corrosion of natural aggregate concrete (NAC) structures, leading to several ...
Faleschini, Flora   +2 more
core   +1 more source

Coefficient Alpha and the Reliability of Composite Measurements [PDF]

open access: yesPsychometrika, 1966
Following a general approach due to Guttman, coefficientα is rederived as a lower bound on the reliability of a test. A necessary and sufficient condition under which equality is attained in this inequality and hence that α is equal to the reliability of the test is derived and shown to be closely related to the recent redefinition of the concept of ...
M R, Novick, C, Lewis
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Coefficient Alpha

open access: yesEurope's Journal of Psychology, 2013
Heavy reliance on Cronbach’s alpha has been standard practice in many validation studies. However, there seem to be two misconceptions about the interpretation of alpha.
Panayiotis Panayides
doaj   +1 more source

Psychometric properties of the king spiritual intelligence questionnaire (KSIQ) in physical veterans of Iran-Iraq warfare [PDF]

open access: yes, 2015
Aims: The study's purpose was to determine reliability and validity of the King spiritual intelligence questionnaires in veterans of Iran-Iraq Warfare. Methods: In this cross sectional study, 300 veterans of the Iran-Iraq war completed the King spiritual
Abbaszadeh, A.   +8 more
core  

The Telehealth Skills, Training, and Implementation Project: An evaluation protocol [PDF]

open access: yes, 2015
External stabilization is reported to improve reliability of hand held dynamometry, yet this has not been tested in burns. We aimed to assess the reliability of dynamometry using an external system of stabilization in people with moderate burn injury and
Barnett, Stephen   +14 more
core   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Cross-cultural adaptation and validation of the “spinal cord injury-falls concern scale” in the Italian population [PDF]

open access: yes, 2018
Study design: Psychometrics study. Objective: The objective of this study was to develop an Italian version of the Spinal Cord Injury-Falls Concern Scale (SCI-FCS) and examine its reliability and validity.
A Citterio   +35 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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