Results 41 to 50 of about 7,151,841 (337)

Coefficient Alpha

Europe's Journal of Psychology, 2013
Heavy reliance on Cronbach’s alpha has been standard practice in many validation studies. However, there seem to be two misconceptions about the interpretation of alpha.
Panayiotis Panayides
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Evaluation of the effluent concentrations of Karbala wastewater treatment plant using reliability analysis

Open Engineering
The effective and consistent operation of wastewater treatment plant systems (WWTPs) is crucial for the sustainability of the environment and public health protection.
Atea Ruqayah Fadhil, Al-Saadi Riyadh Jasim Mohammed, Al-Baidhani Jabbar H., Hassan Waqed H.   +3 more
doaj   +1 more source

Reliability and validity of lower limb joint range of motion measurements using a smartphone [PDF]

, 2022
This study aimed to examine the reliability and validity of using a smartphone to measure the multi-joint range of motion of the lower limbs. We measured the straight leg raise angle, ankle dorsiflexion angle, and hip internal rotation angle in each of ...
Miyachi, Yousuke, Kamiya, Mitsuhiro, Ban, Rua, Furuta, Kunihiro, Hanamura, Shuntaro, Ito, Morihiro   +5 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Validity and Reliability of the Thai Version of the Thyroid-Related Patient-Reported Outcome—A Thyroid-specific Quality of Life Questionnaire

International Archives of Otorhinolaryngology, 2021
Introduction The Thyroid-Related Patient-Reported Outcome (ThyPRO) is a new thyroid-specific quality of life patient-reported outcome measure for benign thyroid disorders.
Patorn Piromchai, Supachat Chaiudomsom, Pattaramon Wijakkanalan, Torquil Watt   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

What Is the Test-Retest Reliability of Common Task-Functional MRI Measures? New Empirical Evidence and a Meta-Analysis

Psychology Science, 2020
Identifying brain biomarkers of disease risk is a growing priority in neuroscience. The ability to identify meaningful biomarkers is limited by measurement reliability; unreliable measures are unsuitable for predicting clinical outcomes.
Maxwell Lorenz Elliott, A. Knodt, D. Ireland, Meriwether L. Morris, R. Poulton, S. Ramrakha, Maria L. Sison, T. Moffitt, A. Caspi, A. Hariri   +9 more
semanticscholar   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Research on Screening Method of Loess Slope Stability Evaluation Indexes Based on Validity and Reliability Coefficient

Applied Sciences
Aiming at the problems of intense subjectivity and high redundancy in the screening of indicators in the stability evaluation of loess slopes, this study proposes an evaluation method integrating the validity and reliability coefficients.
Jianlong Liao, Hongjun Sun, Jianchao An
doaj   +1 more source