Results 51 to 60 of about 1,364,177 (309)

Evaluation of the effluent concentrations of Karbala wastewater treatment plant using reliability analysis

open access: yesOpen Engineering
The effective and consistent operation of wastewater treatment plant systems (WWTPs) is crucial for the sustainability of the environment and public health protection.
Atea Ruqayah Fadhil   +3 more
doaj   +1 more source

Validity and Reliability of an Inertial Device for Measuring Dynamic Weight-Bearing Ankle Dorsiflexion [PDF]

open access: yes, 2020
A decrease in ankle dorsiflexion causes changes in biomechanics, and different instruments have been used for ankle dorsiflexion testing under static conditions.
Martín Fuentes, Isabel   +2 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The reliability and validity of a designed setup for the assessment of static back extensor force and endurance in older women with and without hyperkyphosis. [PDF]

open access: yes, 2018
ObjectiveThe purpose of this study was to investigate the intra-rater reliability and validity of a designed load cell setup for the measurement of back extensor muscle force and endurance.ParticipantsThe study sample included 19 older women with ...
Akbarzadeh Baghban, Alireza   +7 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Research on Screening Method of Loess Slope Stability Evaluation Indexes Based on Validity and Reliability Coefficient

open access: yesApplied Sciences
Aiming at the problems of intense subjectivity and high redundancy in the screening of indicators in the stability evaluation of loess slopes, this study proposes an evaluation method integrating the validity and reliability coefficients.
Jianlong Liao, Hongjun Sun, Jianchao An
doaj   +1 more source

Importance sampling the union of rare events with an application to power systems analysis

open access: yes, 2018
We consider importance sampling to estimate the probability $\mu$ of a union of $J$ rare events $H_j$ defined by a random variable $\boldsymbol{x}$. The sampler we study has been used in spatial statistics, genomics and combinatorics going back at least ...
Chertkov, Michael   +2 more
core   +1 more source

The inter- and intra-observer reliability of a locomotion scoring scale for sheep [PDF]

open access: yes, 2008
A seven point locomotion scoring scale, ranging from 0 = normal locomotion to 6 = unable to stand or move, has been developed. To test the between and within observer reliability of the scale, 65 movie clips of sheep with normal and varying degrees of ...
Green, Laura E.   +2 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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