Results 91 to 100 of about 1,372,986 (292)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Bayesian Estimation for Reliability Engineering: Addressing the Influence of Prior Choice. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Leoni L   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

On certain functionals of normal processes Technical report no. 1 [PDF]

open access: yes
Probabilistic modeling and stochastic process investigations to provide measures of quality of performance and reliability for systems engineering - Chebyshev ...
Cryer, J. D., Leadbetter, M. R.
core   +1 more source

Report on visit to four North American airlines [PDF]

open access: yes, 1965
The object of the visits was to discuss the current state-of-the-art with the Engineering Departments of several North American airlines which were known to be leading the field in the application of certain advanced techniques.
Hyde, D.
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Rationale for structural inspections [PDF]

open access: yes
The methods developed to predict the reliability of aircraft structures depend upon inspection effectiveness which, in turn, depends upon structural complexity, quality, and the percentage of the structure inspected.
Davidson, J. R.
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

A Reliability Engineering Approach for Managing Risks in CubeSats

open access: yesAerospace, 2018
Besides large-scale space missions, the spread of CubeSats for a variety of applications is increasingly requiring the development of systematic approaches for risk management.
Alessandro Menchinelli   +6 more
doaj   +1 more source

Solution of geometrically nonlinear statics problems by the p-version of the finite element method [PDF]

open access: yes
This project is concerned with the possibility of using computers for the simulation of structural systems with the same degree of reliability as full scale physical experiments.
Szabo, Barna A.
core   +1 more source

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