Results 71 to 80 of about 1,372,986 (292)
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Due to its advantages of small size and light weight, multi-pulse rectifier has a broad application prospect in the field of aviation. The 18-pulse rectifier is more popular in practical engineering application because of its better rectifier ...
Yingying Zhang +6 more
doaj +1 more source
Affordances and Safe Design of Assistance Wearable Virtual Environment of Gesture [PDF]
Safety and reliability are the main issues for designing assistance wearable virtual environment of technical gesture in aerospace, or health application domains.
Fass, Didier
core +5 more sources
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Anomaly detection in a fleet of industrial assets with hierarchical statistical modeling
Anomaly detection in asset condition data is critical for reliable industrial asset operations. But statistical anomaly classifiers require certain amount of normal operations training data before acceptable accuracy can be achieved.
Maharshi Dhada +2 more
doaj +1 more source
Statistical modelling of software reliability [PDF]
During the six-month period from 1 April 1991 to 30 September 1991 the following research papers in statistical modeling of software reliability appeared: (1) A Nonparametric Software Reliability Growth Model; (2) On the Use and the Performance of ...
Miller, Douglas R.
core +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Application of a truncated normal failure distribution in reliability testing [PDF]
Statistical truncated normal distribution function is applied as a time-to-failure distribution function in equipment reliability estimations. Age-dependent characteristics of the truncated function provide a basis for formulating a system of high ...
Groves, C., Jr.
core +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source

