Results 101 to 110 of about 327,842 (293)

An enzyme‐linked immunosorbent assay (ELISA)‐based activity assay for AMP‐activated protein kinase (AMPK)

FEBS Open Bio, EarlyView.
Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley   +1 more source

Employing Software Diversity in Cloud Microservices to Engineer Reliable and Performant Systems [PDF]

arXiv
In the ever-shifting landscape of software engineering, we recognize the need for adaptation and evolution to maintain system dependability. As each software iteration potentially introduces new challenges, from unforeseen bugs to performance anomalies, it becomes paramount to understand and address these intricacies to ensure robust system operations ...
arxiv  

Handbook of Reliability Engineering [PDF]

, 1994
Necip Doganaksoy, Igor Ushakov, Robert A. Harrison   +2 more
openalex   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Quality, reliability and re‐engineering [PDF]

, 1994
P. D. T. O’Connor
openalex   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Engineering Reliability of Navigation Structures [PDF]

, 1992
Thomas F. Wolff, Weijun Wang
openalex   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

International Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Hierarchical Bayesian Modeling for Uncertainty Quantification and Reliability Updating using Data [PDF]

arXiv
Quantifying uncertainty and updating reliability are essential for ensuring the safety and performance of engineering systems. This study develops a hierarchical Bayesian modeling (HBM) framework to quantify uncertainty and update reliability using data.
arxiv  

Finite State Machine Based Evaluation Model for Web Service Reliability Analysis [PDF]

arXiv, 2011
Now-a-days they are very much considering about the changes to be done at shorter time since the reaction time needs are decreasing every moment. Business Logic Evaluation Model (BLEM) are the proposed solution targeting business logic automation and facilitating business experts to write sophisticated business rules and complex calculations without ...
arxiv