Results 51 to 60 of about 4,984,516 (327)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Heuristic Hybrid Optimization Approach for Spare Parts and Maintenance Workers Under Partial Pooling

open access: yesIEEE Access, 2019
The joint planning of spare parts and maintenance workers in a multiple echelon inventory system with lateral and cross-echelon transshipment can reduce the total cost of the system.
Bowen Cui   +6 more
doaj   +1 more source

Finite element model updating of a RC building considering seismic response trends [PDF]

open access: yes, 2013
ACKNOWLEDGEMENTS The authors would like to thank their supporters. GeoNet staff, particularly Dr Jim Cousins, Dr S.R. Uma and Dr Ken Gledhill, helped with access to seismic data and building information.
Butt, F., Omenzetter, P.
core   +1 more source

Prompt engineering in consistency and reliability with the evidence-based guideline for LLMs

open access: yesnpj Digit. Medicine
The use of large language models (LLMs) in clinical medicine is currently thriving. Effectively transferring LLMs’ pertinent theoretical knowledge from computer science to their application in clinical medicine is crucial.
Li Wang   +7 more
semanticscholar   +1 more source

Classification of indicators of reliability of systems in heavy engineering

open access: yes, 2021
A feature of this work is the study of the design reliability assessment based on analytical data, with further classification of its indicators. Like any other properties of technical devices, reliability is assessed by a certain set of indicators.
V. A. Golikov
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Optimal Design of Accelerated Life Test Plan for Test Standard of a Manufacturer Making Multi-Series Products

open access: yesIEEE Access, 2019
To win fierce competition, a manufacturer would produce multi-series products to meet the diverse needs of customers. These products shall comply with the same test standard to estimate reliability before being launched into market.
Zixuan Pei, Yunxia Chen, Kunsong Lin
doaj   +1 more source

System Modeling and Fault Tree Analysis Based on AltaRica

open access: yesIEEE Access, 2020
With the increasing scale and complexity of system, it is very necessary to analyze the safety of complex system. Fault tree is an effective method to safety analysis. However, traditional fault tree relies on manual construction and analysis. When fault
Zhen Li   +3 more
doaj   +1 more source

A Reliability Engineering Approach for Managing Risks in CubeSats

open access: yesAerospace, 2018
Besides large-scale space missions, the spread of CubeSats for a variety of applications is increasingly requiring the development of systematic approaches for risk management.
Alessandro Menchinelli   +6 more
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

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