Results 71 to 80 of about 4,984,516 (327)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Prognostic and Remaining Life Prediction of Electronic Device under Vibration Condition Based on CPSD of MPI

open access: yesShock and Vibration, 2016
Prognostic of electronic device under vibration condition can help to get information to assist in condition-based maintenance and reduce life-cycle cost.
Ying Chen, Ning Tang, Zenghui Yuan
doaj   +1 more source

A Comprehensive Review of Research Hotspots on Battery Management Systems for UAVs

open access: yesIEEE Access, 2023
Battery-powered unmanned aerial vehicles (UAVs), also known as drones, have emerged as the primary choice in the UAV market. The UAV Battery Management System (BMS) performs critical functions such as charging and discharging control, state detection ...
Shiqin Jiao   +3 more
doaj   +1 more source

Reliability Analysis Model [PDF]

open access: yes, 1970
RAM program determines probability of success for one or more given objectives in any complex system. Program includes failure mode and effects, criticality and reliability analyses, and some aspects of operations, safety, flight technology, systems ...

core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Improving the foundation and practice of reliability engineering

open access: yes, 2017
Reliability engineering is today a well-established field, accounting for many scientific journals and conferences, educational programmes and courses, academic positions and societies.
T. Aven
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Analysis of University Students’ Behavior Based on a Fusion K-Means Clustering Algorithm

open access: yesApplied Sciences, 2020
With the development of big data technology, creating the ‘Digital Campus’ is a hot issue. For an increasing amount of data, traditional data mining algorithms are not suitable. The clustering algorithm is becoming more and more important in the field of
Wenbing Chang   +6 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

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