Results 61 to 70 of about 2,268,235 (274)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Psychometric Evaluation and Design of Patient-Centered Communication Measures for Cancer Care Settings [PDF]

, 2017
Objective To evaluate the psychometric properties of questions that assess patient perceptions of patient-provider communication and design measures of patient-centered communication (PCC). Methods Participants (adults with colon or rectal cancer living
Bann, Carla M., He, Jason, Jackson, Kathryn D., Mack, Nicole, Magnus, Brooke E., Mann, Courtney, McCormack, Lauren A., Moultrie, Rebecca, Reeve, Bryce B., Roach, Nancy, Sanoff, Hanna K., Thissen, David M., Treiman, Katherine, Wagner, Laura K.   +13 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Calculations of System Aging through the Stochastic Entropy

Entropy, 2006
The present research discusses four ‘physical’ models of system and calculates thereliability function during system’s aging and maturity on the basis of the system structure.
Paolo Rocchi
doaj   +1 more source

Psychometric Evaluation of the Physical Activity Enjoyment Scale in Adults with Functional Limitations [PDF]

, 2016
Enjoyment is an important construct for understanding physical activity participation, and it has not been examined in adults with functional limitations.
Bekhet, Abir K., Murrock, Carolyn J., Zauszniewski, Jaclene A.   +2 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

The Method of Types for the AWGN Channel

Entropy
For the discrete-time AWGN channel with a power constraint, we give an alternative derivation for the sphere-packing upper bound on the optimal block error exponent and an alternative derivation for the analogous lower bound on the optimal correct ...
Sergey Tridenski, Anelia Somekh-Baruch
doaj   +1 more source

Estimation of the two-parameter Weibull distribution parameters using the coefficient of variation

Vojnotehnički Glasnik, 1996
This paper presents a method for estimating the reliability function parameters when reliability function is the 2-parametar Weibull regression. This model is often used in a reliability analysis in wide variety of situations to approximate successfully ...
Slavko Tomović
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Reliability Estimation for Burr XII Distribution under the Weighted Q-Symmetric Entropy Loss Function

Applied Sciences
Considering that the choice of loss function plays a significant role in the derivation of Bayesian estimators, we propose a novel asymmetric loss function named the weighted Q-symmetric entropy loss for computing the estimates of the parameter and ...
Kexin He, Wenhao Gui
doaj   +1 more source