Results 131 to 140 of about 1,358,459 (299)
Intraday reliability, sensitivity, and minimum detectable change of national physical fitness measurement for preschool children in China. [PDF]
PLoS One, 2020 Fang H, Ho IMK.
europepmc +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
THE INFLUENCE OF ACCOUNTING STUDENT MORAL REASONING AND ETHICAL SENSITIVITY TOWARD UNETHICAL ACADEMIC BEHAVIOUR [PDF]
, 2017 In the context of education in Indonesia, the phenomenon about the deterioration of moral values has become a kind of red light urging all parties, to immediately see an important synergy for the development of character education.
AZZAHRA, Ristya Annisya, HARTO, Puji
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Exploring sensitive skin to design reliable measurements
Skin Research and Technology, 2023 Juliette Rengot +8 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Sensitivity Analysis of the Locus Reliability of Linear Motion Mechanism
Jixie chuandong, 2016 To improve the locus accuracy of linear motion mechanism with uncertainty factor,the analytical algorithm of locus reliability sensitivity analysis for linear motion mechanism is presented.
Wu Jiping, He Bing, Hu Weilin
doaj