Results 41 to 50 of about 1,887,642 (299)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Storage Reliability Assessment Method for Aerospace Electromagnetic Relay Based on Belief Reliability Theory

open access: yesApplied Sciences, 2022
The aerospace electromagnetic relay (AEMR) is a key electronic component in aerospace and weaponry systems. It usually lacks sufficient test data to conduct an effective storage reliability assessment at its early development stage.
Qingshen Li   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

L-Band Vegetation Optical Depth Estimation Using Transmitted GNSS Signals: Application to GNSS-Reflectometry and Positioning

open access: yesRemote Sensing, 2020
At L-band (1–2 GHz), and particularly in microwave radiometry (1.413 GHz), vegetation has been traditionally modeled with the τ-ω model. This model has also been used to compensate for vegetation effects in Global Navigation Satellite Systems ...
Adriano Camps   +5 more
doaj   +1 more source

Research on Embedded Dual Operating System Architecture Based on Trusted Execution Environment [PDF]

open access: yesJisuanji gongcheng, 2019
To address the requirements of the embedded systems for functionality and real-time performance,this paper presents a dual operating system architecture.Based on the trusted execution environment provided by ARM TrustZone,the dual operating system ...
MENG Ziqi,ZHANG Qianying,SHI Zhiping,GUAN Yong
doaj   +1 more source

Marker effects and examination reliability: a comparative exploration from the perspectives of generalizability theory, Rasch modelling and multilevel modelling [PDF]

open access: yes, 2013
This study looked at how three different analysis methods could help us to understand rater effects on exam reliability. The techniques we looked at were: generalizability theory (G-theory) item response theory (IRT): in particular the Many-Facets ...
Baird, Jo-Anne   +4 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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