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Lomax–Bilal Distribution Within the Bilal-G Family: Theoretical Properties and Applications
MathematicsIn this paper, we propose a new flexible modification of the Lomax distribution within the Bilal-G family generated through the T-X framework, referred to as the Lomax–Bilal distribution.
Ghadah Alomani, Amer Ibrahim Al-Omari
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
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Analysis of the Component-Based Reliability in Computer Networks
Cubo, 2010 Performance in terms of reliability of computer networks motivates this paper. Limit theorems on the extreme queue length and extreme virtual waiting time in open queueing networks in heavy traffic are derived and applied to a reliability model for ...
Saulius Minkevi<img width=12 height=19 src="http:/fbpe/img/cubo/v12n1/img27.jpg">ius
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Probabilistic method to determine the overall rock block failure based on failure mode
Engineering Transactions, 2016 In rock slopes or underground excavations, due to the structure of the cutting surface, rock typically exhibits strong random properties, such as the structure of the surface geometry and mechanical parameters showed strong randomness, resulting in a ...
Hongze ZHAO, Zequan LI, Chi Seng KONG
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Fuzzy Reliability Theory Based on Membership Function [PDF]
International Journal of Mathematical, Engineering and Management Sciences, 2016 In this study, it is considered that the shape of membership function and the values of parameters are arbitrary, hence reliability parameters will be arbitrary, and some data are even absurd from the point of view of real life practice. An applied fuzzy
Shshank Chaube, S. B. Singh
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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Reliability in the theory of management of socio-economic systems. [PDF]
, 2012 This paper focuses on the concept of reliability from the management point of view and the possibility of its adaptation to the socio-economic ...
Taran-Lala, Оlena +3 more
core
IEEE Access, 2019 Risk priority number (RPN) is a widely used approach, and it is a powerful means to assess the criticality of modes in a failure modes, effects, and criticality analysis (FMECA) worksheet.
Lorenzo Ciani +2 more
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