Results 61 to 70 of about 1,887,642 (299)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Analysis of the Component-Based Reliability in Computer Networks

open access: yesCubo, 2010
Performance in terms of reliability of computer networks motivates this paper. Limit theorems on the extreme queue length and extreme virtual waiting time in open queueing networks in heavy traffic are derived and applied to a reliability model for ...
Saulius Minkevi<img width=12 height=19 src="http:/fbpe/img/cubo/v12n1/img27.jpg">ius
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

A Critical Comparison of Alternative Risk Priority Numbers in Failure Modes, Effects, and Criticality Analysis

open access: yesIEEE Access, 2019
Risk priority number (RPN) is a widely used approach, and it is a powerful means to assess the criticality of modes in a failure modes, effects, and criticality analysis (FMECA) worksheet.
Lorenzo Ciani   +2 more
doaj   +1 more source

Psychometric Evaluation and Design of Patient-Centered Communication Measures for Cancer Care Settings [PDF]

open access: yes, 2017
Objective To evaluate the psychometric properties of questions that assess patient perceptions of patient-provider communication and design measures of patient-centered communication (PCC). Methods Participants (adults with colon or rectal cancer living
Bann, Carla M.   +13 more
core   +1 more source

The Basic Psychological Needs in Exercise Scale: Translation and Evidence for Cross-Cultural Validity [PDF]

open access: yes, 2010
The present study reports on the psychometric evaluation and cross-cultural validity of the Basic Psychological Needs in Exercise Scale (BPNES; Vlachopoulos & Michailidou, 2006) translated from Greek into English.
Ntoumanis, Nikos   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

HEAP: An Efficient and Fault-Tolerant Authentication and Key Exchange Protocol for Hadoop-Assisted Big Data Platform

open access: yesIEEE Access, 2018
Hadoop framework has been evolved to manage big data in cloud. Hadoop distributed file system and MapReduce, the vital components of this framework, provide scalable and fault-tolerant big data storage and processing services at a lower cost.
Durbadal Chattaraj   +5 more
doaj   +1 more source

A Parrondo Paradox in Reliability Theory

open access: yes, 2007
Parrondo's paradox arises in sequences of games in which a winning expectation may be obtained by playing the games in a random order, even though each game in the sequence may be lost when played individually. We present a suitable version of Parrondo's
Di Crescenzo, Antonio
core  

Mathematical techniques for estimating operational readiness of complex systems [PDF]

open access: yes, 1972
Development of methods for predicting operational readiness of complex systems based on probability theory is discussed. Operational readiness of systems is defined and mathematical relationships involved in determining readiness are presented.
Jacquier, I. D., Miltz, P. A.
core   +1 more source

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