Results 61 to 70 of about 6,815,023 (244)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Split Reliability

, 2021
The split reliability of a graph G is the probability that if every edge is independently operational with probability p, every vertex is always operational, and we specify two vertices s and t, that every vertex can communicate with exactly one of s or ...
McMullin, Isaac
core  

HEAP: An Efficient and Fault-Tolerant Authentication and Key Exchange Protocol for Hadoop-Assisted Big Data Platform

IEEE Access, 2018
Hadoop framework has been evolved to manage big data in cloud. Hadoop distributed file system and MapReduce, the vital components of this framework, provide scalable and fault-tolerant big data storage and processing services at a lower cost.
Durbadal Chattaraj, Monalisa Sarma, Ashok Kumar Das, Neeraj Kumar, Joel J. P. C. Rodrigues, Youngho Park   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The usefulness of complete lattices in reliability theory

, 1995
The main aim of this paper is to show how lattice theory in the very next future will be a useful tool in analysing complex real reliability problems, not properly modelled within classical reliability theory.
Montero, J., Kerre, Etienne, Kerre, Etienne E., Montero De Juan, Francisco Javier, Etienne E. Kerre, Javier Montero, Bart Cappelle, Cappelle, Bart   +7 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Graph Theory Based Reliability Assessment Software Program for Complex Systems

, 2019
Reliability is a conceptual term that means endurance, dependability, andgood performance. However, in system engineering, it is more than a conceptualterm; it can be measured and evaluated.
Abdrabbi Bourezg, Bentarzi, Hamid, Hamid Bentarzi, Bourezg, Abdrabbi   +3 more
core   +1 more source

Trading reliability targets within a supply chain using Shapley's value [PDF]

, 2007
The development of complex systems involves a multi-tier supply chain, with each organisation allocated a reliability target for their sub-system or component part apportioned from system requirements.
Quigley, John, Walls, Lesley
core   +2 more sources