Results 71 to 80 of about 1,877,205 (300)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Reliability approach to rotating-component design [PDF]

A probabilistic methodology for designing rotating mechanical components using reliability to relate stress to strength is explained. The experimental test machines and data obtained for steel to verify this methodology are described. A sample mechanical
Kececioglu, D. B., Lalli, V. R.
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Mathematical techniques for estimating operational readiness of complex systems [PDF]

, 1972
Development of methods for predicting operational readiness of complex systems based on probability theory is discussed. Operational readiness of systems is defined and mathematical relationships involved in determining readiness are presented.
Jacquier, I. D., Miltz, P. A.
core   +1 more source

Multilevel Monte Carlo for Reliability Theory

Reliability Engineering & System Safety, 2017
As the size of engineered systems grows, problems in reliability theory can become computationally challenging, often due to the combinatorial growth in the cut sets. In this paper we demonstrate how Multilevel Monte Carlo (MLMC) - a simulation approach which is typically used for stochastic differential equation models - can be applied in reliability ...
Aslett, L. J. M., Nagapetyan, T., Vollmer, S. J.   +2 more
openaire   +4 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Reliability and Responsibility: A Theory of Endogenous Commitment [PDF]

A common assumption in Political Science literature is policy commitment: candidates maintain their electoral promises. We drop such assumption and we show that costless electoral campaign can be an effective way of transmitting information to voters ...
Matteo Triossi
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Reliability Beyond Theory and Into Practice [PDF]

Psychometrika, 2009
The critical reactions of Bentler (2009, doi:10.1007/s11336-008-9100-1), Green and Yang (2009a, doi:10.1007/s11336-008-9098-4; 2009b, doi:10.1007/s11336-008-9099-3), and Revelle and Zinbarg (2009, doi:10.1007/s11336-008-9102-z) to Sijtsma’s (2009, doi:10.1007/s11336-008-9101-0) paper on Cronbach’s alpha are addressed.
openaire   +4 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Calculation of road reliability based on mathematical theory of reliability

MATEC Web of Conferences, 2018
The paper presents the mathematical theory of reliability as related to the theory of road reliability. The concepts of “initial reliability” and “durability” are combined in a single algorithm.
Efimenko Vladimir, Moisejenko Rostislav
doaj   +2 more sources

On the Estimation of Cost of Capital and its Reliability [PDF]

Gordon and Shapiro (1956) first equated the price of a share with the present value of future dividends and derived the well-known relationship. Since then, there have been many improvements on the theory. For example, Thompson (1985, 1987) combined the "
Raymond H. Chan, Wing-Keung Wong
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