Results 41 to 50 of about 1,909,128 (290)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Development of A Floating Market-Based BioPhy Magazine to Train the Religious Characters of Pre-Service Science Teachers

Tadris: Jurnal Keguruan dan Ilmu Tarbiyah, 2022
This study aimed to describe the validity of the integration of religious values in BioPhy magazine and the religious character of pre-service science teachers when using the Floating Market-based BioPhy magazine.
Lutfiyanti Fitriah, Ita Ita
doaj   +1 more source

Pendidikan Karakter melalui Pendidikan Agama Islam di Era Revolusi Digital

Intelektual, 2022
The emergence of increasingly sophisticated technology requires humans to optimize intellectually and morally. Education plays a role in producing a generation of intellectuals and noble characters.
Ummi Kulsum, Abdul Muhid
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Religious Studies and Transcultural Studies:: Revealing a Cosmos Not Known Before? [PDF]

, 2016
Drawing on our research on Pentecostal Christianity in Singapore, the article introduces the transcultural approach and discusses its possible contributions to the academic study of religions.
Katja Rakow, Berg, Esther, OFR - Religious Studies, Esther Berg, Rakow, K., LS Religiewetenschap   +5 more
core   +2 more sources

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

Arthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni, Lee Shapiro, Deana Gibbs, Zsuzsanna H. McMahan, Michael Hughes   +4 more
wiley   +1 more source

NILAI PENDIDIKAN KARAKTER RELIGIUS NOVEL RANTAU 1 MUARA KARYA AHMAD FUADI

Potensia, 2019
This study aims to describe the values of religious character breeding in novel Rantau 1 Muara by Ahmad Fuadi. Novel Rantau 1 Muara is a novel that clearly tells of a value of struggle, persistence, obedience to God and a view of life that intends to ...
Rahmat Gunawan, Suyitno Suyitno, Slamet Supriyadi   +2 more
doaj   +1 more source

Clinician and Patient Factors Associated With Long‐Term Glucocorticoid Use in People With Rheumatoid Arthritis Receiving Advanced Therapies

Arthritis Care &Research, EarlyView.
Objective Despite guideline recommendations, long‐term glucocorticoid (GC) use is common in rheumatoid arthritis (RA). We conducted a clinician survey nested within a large registry to identify patient and clinician factors associated with GC use. Methods Clinicians contributing patients to the CorEvitas Rheumatoid Arthritis Registry were surveyed ...
Michael D. George, George Reed, Matthew D. Kearney, Peter F. Cronholm, Kevin Kane, Jeffrey R. Curtis, Dimitrios A. Pappas, Joel M. Kremer   +7 more
wiley   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Conceptualizing and Measuring Religious Development in Terms of Religious Styles and Schemata; New Considerations [PDF]

, 2010
Streib H. Conceptualizing and Measuring Religious Development in Terms of Religious Styles and Schemata; New Considerations. Presented at the Conference "Psychologie du développement religieux: questions classiques et perspectives contemporairnes ...
Streib, Heinz ; https://orcid.org/
core